Best UFC 303 Co-Main Event Betting Picks: Brian Ortega vs Diego Lopes

  • What: UFC 303 Co-Main Event
  • Who: Brian Ortega vs Diego Lopes
  • Date: Saturday, June 29, 2024
  • Location: T-Mobile Arena in Las Vegas, Nevada
  • Time: Early Prelims (6:00 p.m. ET), Prelims (8:00 p.m. ET), Pay-Per-View Card (10:00 p.m. ET)
  • How to Watch:  Early Prelims (ESPN+) Prelims (ESPN), Main Card (ESPN+ PPV)

With the injury to Conor McGregor, UFC 303 got a new main event. A broken toe knocked McGregor out of his scheduled UFC 303 bout against Michael Chandler. With that highly-anticipated contest off the card, the UFC booked a rematch between UFC light heavyweight champion Alex Pereira and former titleholder Jiri Prochazka to headline the June 29 fight card that takes place at T-Mobile Arena in Las Vegas. An injury to Jamahal Hill and a drug test failure from Khalil Rountree resulted in the event losing its co-main event as well. The new UFC 303 co-headlining contest sees former UFC featherweight title challenger Brian Ortega facing the rising Diego Lopes. Here is some background on Ortega and Lopes before we look at the betting breakdown for UFC 303.

Brian Ortega (16-3-0-1) is the No. 3 fighter in the official UFC featherweight rankings. Ortega has fought twice for the UFC’s 145-pound title, losing to Max Holloway and Alexander Volkanovski. He is coming off a February submission win over Yair Rodriguez.

Diego Lopes (24-6) is ranked at No. 14 in the UFC 145-pound weight division. Lopes is on a three-fight winning streak and coming off an April TKO victory over Sodiq Yusuff. UFC 303 is an enormous step up in competition for Lopes.

Before we look at the best bets for Brian Ortega vs Diego Lopes on the UFC 303 PPV card,  check out the best UFC betting sites and the best bets for UFC 303’s main event.

UFC 303 Co-main event: Brian Ortega vs Diego Lopes betting picks

FightersBetOnline ReviewBovadaBetUS ReviewMyBookie Review
Diego Lopes-145-150-145-147
Brian Ortega+125+125+115+115

Brian Ortega betting breakdown

Brian Ortega is a tough fighter with a solid chin. His two TKO losses have come by way of injury and doctor stoppage, so count on him to be in this fight until the end. Ortega is a top-notch grappler with eight submission wins, but his takedown accuracy is just 27 percent, which is low. However, he has good cardio, and he can string takedown attempts together until he gets the fight to the mat.

Ortega is a pressure striker. He lands 4.07 significant strikes per minute, but his defense is lacking and he absorbs 6.54 significant strikes per minute, which is a worry against someone like Lopes, who is coming off two TKO wins in a row.

Ortega has been with the UFC 2014 and has been inside the cage with some of the best fighters in the UFC’s featherweight division. That level of experience will come into play in this fight. There’s nothing the 33-year-old Ortega hasn’t seen inside the Octagon.

What makes Ortega so dangerous is that he never quits. He can be far behind on the scorecards and still be a threat to pick up a win via stoppage.

Brian OrtegaTO BEAT DIEGO LOPES
★★★★★
+125
Bet now

Diego Lopes betting breakdown

At 29, Diego Lopes has been with the UFC since May 2023. He lost his UFC debut, dropping a decision to Movsar Evloev, but since that setback, Lopes is 3-0 with three first-round stoppage wins. He has only gone the distance six times in his career, winning two of those bouts and losing four. Of his wins, 10 have come by knockout and 12 via submission. His two other losses are both by knockout.

Lopes is a dangerous grappler with a wealth of talent on the mat. He has heavy hands and he is a fighter who wants to get a finish every time he steps into the Octagon. He throws a lot of combinations and he uses pressure on the feet. However, he can sometimes get a bit wild with his striking. Lopes lands 3.22 significant strikes per minute with an accuracy of 58 percent. He absorbs 4.73 significant strikes per minute.

UFC 303 will be a huge opportunity for Lopes to make a massive jump up the UFC featherweight rankings. He has all the tools to compete at the top of the division, and although he doesn’t have the high-level experience of Ortega, he does have more fights than his opponent on this card.

The question Lopes must answer in Las Vegas is if he can deal with someone like Ortega, who will be in his face for the entirety of their matchup.

Diego LopesTO BEAT BRIAN ORTEGA
★★★★★
-150
Bet now

Best Bets – UFC 303 Co-Main Event: Brian Ortega vs Diego Lopes

This fight was not initially on the UFC 303 fight card. When McGregor vs. Chandler was scrapped because of injury, Brian Ortega vs. Diego Lopes was added to the pay-per-view event on short notice. With that, neither man will get much of a training camp, which is something to consider when looking at making a wager on the UFC 303 fight card.

Ortega is resilient and tough, but he takes a lot of damage. If Lopes can pace himself and not get too aggressive in looking for a finish, this fight is his to lose. The betting pick is for Diego Lopes to win via decision or a late doctor stoppage.

Diego LopesTO BEAT BRIAN ORTEGA
★★★★★
-145
Bet now

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Trent Reinsmith

Trent is a professional sports journalist specializing in UFC, MMA, and esports coverage. His work has been featured in prestigious publications such as USA Today Sports, Vice, Bloody Elbow, Fight! Magazine, UFC 360, and Narratively. Trent's connection to MMA dates back to the early days when he and his friends pooled their resources to purchase the pay-per-view broadcast of UFC 1. He also has extensive experience in esports, particularly League of Legends and Counter Strike, dating back to the game's launch.